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Literature summary for 3.5.1.98 extracted from

  • Tong, J.J.; Liu, J.; Bertos, N.R.; Yang, X.J.
    Identification of HDAC10, a novel class II human histone deacetylase containing a leucine-rich domain (2002), Nucleic Acids Res., 30, 1114-1123.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.5.1.98

Inhibitors

Inhibitors Comment Organism Structure
trichostatin A
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm enrichment of enzyme is cytoplasm is not sensitive to leptomycin B Homo sapiens 5737
-

Organism

Organism UniProt Comment Textmining
Homo sapiens Q969S8 isoform HDAC10, class II enzyme
-

Source Tissue

Source Tissue Comment Organism Textmining
293 cell
-
 Homo sapiens
-
HEK-293T cell
-
 Homo sapiens
-
HeLa cell
-
 Homo sapiens
-
HeLa-S3 cell
-
 Homo sapiens
-
kidney
-
 Homo sapiens
-
liver
-
 Homo sapiens
-
pancreas
-
 Homo sapiens
-
ROS 17/2.8 cell
-
 Homo sapiens
-
spleen
-
 Homo sapiens
-

Subunits

Subunits Comment Organism
More enzyme has a bipartite modular structure consisting of a N-terminal putative deacetylase domain and a C-terminal leucine-rich domain. Isoform HDAC10 interacts with enzyme isoform HDAC3, but not with HDAC4 or HDAC6 Homo sapiens