Activating Compound | Comment | Organism | Structure |
---|---|---|---|
NH4+ | no effect | Rattus norvegicus | |
phosphate | - |
Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
NH4+ | no effect | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
2.07 | - |
Gln | in presence of 50 mM phosphate | Rattus norvegicus | |
2.42 | - |
Gln | without phosphate | Rattus norvegicus | |
2.6 | - |
L-Gln | - |
Rattus norvegicus | |
2.6 | - |
Gln | in presence of 10 mM phosphate | Rattus norvegicus | |
2.63 | - |
Gln | in presence of 100 mM phosphate | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Gln + H2O | Rattus norvegicus | high glutaminase activity may be of importance for optimal insulin secretion elicited by amino acid secretagogues | L-Glu + NH3 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HIT-T15 cell | - |
Rattus norvegicus | - |
pancreas | - |
Rattus norvegicus | - |
pancreatic islet | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gln + H2O | - |
Rattus norvegicus | Glu + NH3 | - |
? | |
L-Gln + H2O | high glutaminase activity may be of importance for optimal insulin secretion elicited by amino acid secretagogues | Rattus norvegicus | L-Glu + NH3 | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | 8.5 | - |
Rattus norvegicus |