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Literature summary for 3.5.1.2 extracted from

  • Swierczynski, J.; Bereznowski, Z.; Makarewicz, W.
    Phosphate-dependent glutaminase of rat skeletal muscle. Some properties and possible role in glutamine metabolism (1993), Biochim. Biophys. Acta, 1157, 55-62.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Homo sapiens 5739
-
mitochondrion
-
Rattus norvegicus 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Gln + H2O Homo sapiens
-
L-Glu + NH3
-
?
L-Gln + H2O Rattus norvegicus kidney enzyme increases during acidosis, skeletal muscle enzyme does not. Under some conditions the enzyme from skeletal muscle is able to catabolize Gln to Glu and further to CO2 L-Glu + NH3
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
diaphragm
-
Rattus norvegicus
-
heart
-
Rattus norvegicus
-
skeletal muscle
-
Homo sapiens
-
skeletal muscle
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gln + H2O
-
Homo sapiens Glu + NH3
-
?
Gln + H2O
-
Rattus norvegicus Glu + NH3
-
?
L-Gln + H2O
-
Homo sapiens L-Glu + NH3
-
?
L-Gln + H2O kidney enzyme increases during acidosis, skeletal muscle enzyme does not. Under some conditions the enzyme from skeletal muscle is able to catabolize Gln to Glu and further to CO2 Rattus norvegicus L-Glu + NH3
-
?