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Literature summary for 3.5.1.2 extracted from

  • Kvamme, E.; Olsen, B.E.
    Evidence for two species of mammalian phosphate-activated glutaminase having different regulatory properties (1979), FEBS Lett., 107, 33-36.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Ca2+ 0.5-1.0 mM, NEM-sensitive enzyme Rattus norvegicus
Mersalyl 0.5 mM, almost complete inhibition Rattus norvegicus
Mersalyl 0.5 mM, almost complete inhibition Sus scrofa
NEM enzyme exists as an NEM-sensitive form and an NEM-insensitive form Rattus norvegicus
NEM enzyme exists as an NEM-sensitive form and an NEM-insensitive form Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Rattus norvegicus 5739
-
mitochondrion
-
Sus scrofa 5739
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ 0.5-1.0 mM, 2fold activation of NEM-insensitive enzyme Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Rattus norvegicus
-
brain
-
Sus scrofa
-
kidney
-
Rattus norvegicus
-
kidney
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gln + H2O
-
Rattus norvegicus Glu + NH3
-
?
Gln + H2O
-
Sus scrofa Glu + NH3
-
?