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Literature summary for 3.5.1.19 extracted from

  • Gadd, R.E.A.; Johson, W.J.
    Kinetic studies of nicotinamide deaminase from Micrococcus lysodeikticus (1974), Int. J. Biochem., 5, 397-407.
No PubMed abstract available
Search for more literature for 3.5.1.19

Inhibitors

Inhibitors Comment Organism Structure
5-Methylnicotinamide competitive Micrococcus luteus
EDTA 2 mM, no effect Micrococcus luteus
PCMB
-
 Micrococcus luteus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0029
-
 nicotinamide
-
 Micrococcus luteus
0.36
-
 5'-methylnicotinamide
-
 Micrococcus luteus

Organism

Organism UniProt Comment Textmining
Micrococcus luteus
-
 i.e. Micrococcus lysodeiktikus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-methylnicotinamide + H2O
-
 Micrococcus luteus 5-methylnicotinate + NH3
-
 ?
nicotinamide + H2O
-
 Micrococcus luteus nicotinate + NH3
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
37
-
 stable for more than 3 h Micrococcus luteus
50
-
 10 min, 27% loss of activity Micrococcus luteus
60
-
 10 min, 76% loss of activity Micrococcus luteus

pH Stability

pH Stability pH Stability Maximum Comment Organism
7 9.5 37°C, 10 min, stable Micrococcus luteus