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Literature summary for 3.5.1.19 extracted from
- Nicotinamide deamidase from rabbit liver. 3. Inhibition and sedimentation studies (1973), Arch. Biochem. Biophys., 157, 268-284.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Carbobenzoxyamido-2-phenyl-ethyl-chloromethyl-ketone | - |
Oryctolagus cuniculus |  |
| diisopropylfluorophosphate | - |
Oryctolagus cuniculus | |
| guanidinium hydrochloride | 3.4 M, complete inhibition | Oryctolagus cuniculus | |
| L-thyroxine | - |
Oryctolagus cuniculus | |
| Urea | 8 M, complete inhibition | Oryctolagus cuniculus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 60000 | - |
x * 60000, SDS-PAGE | Oryctolagus cuniculus |
| 211000 | - |
gel filtration | Oryctolagus cuniculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Oryctolagus cuniculus | - |
- |
- |
Oxidation Stability
| Oxidation Stability | Organism |
|---|---|
| photooxidation of two His residues by methylene blue leads to loss of deaminase activity | Oryctolagus cuniculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Oryctolagus cuniculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| nicotinamide + H2O | - |
Oryctolagus cuniculus | nicotinate + NH3 | - |
? | |
| p-nitrophenyl nicotinate + H2O | - |
Oryctolagus cuniculus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 60000, SDS-PAGE | Oryctolagus cuniculus |
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