Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
vasorin + H2O | Homo sapiens | - |
soluble vasorin + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | - |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
MCF-7 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
vasorin + H2O | - |
Homo sapiens | soluble vasorin + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ADAM17 | - |
Homo sapiens |
TACE | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | inhibition of ADAM17 leads to the upregulation of transforming growth factor-beta signaling | Homo sapiens |
physiological function | through the cleavage of vasorin, ADAM17 controls transforming growth factor-beta-mediated epithelial-to-mesenchymal transition | Homo sapiens |