Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
N1E-115 cell | neuroblastoma cell line | Mus musculus | - |
Organism | Comment | Expression |
---|---|---|
Mus musculus | in proliferating cells which are stably transfected to impose the anchorage of a chimeric B12-binding protein, transcobalamin-oleosin TO, to the intracellular membrane, a 2-fold increase of p75NTR-regulated intramembraneous proteolysis is observed that is associated with an increased expression of enzymes Adam-10 and Adam-17 | up |
General Information | Comment | Organism |
---|---|---|
physiological function | vitamin B12 cellular deficiency produces a slower proliferation and a speedier differentiation of neuroblastoma cells through interacting signaling pathways that are related with increased expression of phophatase 2A, pro-nerve growth factor and TACE | Mus musculus |