Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
JURKAT cell | - |
Homo sapiens | - |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | Porphyromonas gingivalis challenge results in a concentration-dependent enhancement of TACE messenger RNA expression and protein release by Jurkat cells. TLCK treatment or heat treatment of Porphyromonas gingivalis culture supernatants decreases TACE release to control levels | up |
General Information | Comment | Organism |
---|---|---|
physiological function | Porphyromonas gingivalis challenge results in a concentration-dependent enhancement of TACE messenger RNA expression and protein release by Jurkat cells. The induction of TACE by T-cells in response to Porphyromonas gingivalis may in turn favour the shedding of host cell-bound cytokines into the local microenvironment, potentially amplifying the inflammatory response | Homo sapiens |