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Literature summary for 3.4.24.86 extracted from
- LRP1 shedding in human brain: Roles of ADAM10 and ADAM17 (2009), Mol. Neurodegener., 4, 17.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| TIMP-3 | presence of TIMP-3 inhibits shedding of lipoprotein-related protein I | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| fibroblast | embryonic fibroblast | Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| lipoprotein-related protein I + H2O | lipoprotein-related protein I shedding is significantly decreased in embryonic fibroblast cells lacking ADAM10 and/or ADAM17 | Mus musculus | ? | - |
? |  |
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Release 2023.1 (January 2023)
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