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Literature summary for 3.4.24.86 extracted from

  • Wu, K.; Liao, M.; Liu, B.; Deng, Z.
    ADAM-17 over-expression in gallbladder carcinoma correlates with poor prognosis of patients (2011), Med. Oncol., 28, 475-480.
    View publication on PubMed

Application

Application Comment Organism
medicine expression of ADAM-17 is significantly increased in gallbladder carcinoma with high histological grade and pT stage compared with low histological grade and pT stage tumors and is not associated with patients’ gender, age, histological type, and resection margin involvement. Patients with high expression of ADAM-17 have a significantly shorter overall survival compared with those with low expression. The prognostic impact of ADAM-17 is independent of conventional prognostic factors for gallbladder carcinoma Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining

Expression

Organism Comment Expression
Homo sapiens expression of ADAM-17 is significantly increased in gallbladder carcinoma with high histological grade and pT stage compared with low histological grade and pT stage tumors and is not associated with patients’ gender, age, histological type, and resection margin involvement up