Literature summary for 3.4.24.86 extracted from

Kirkegaard, T.; Naresh, A.; Sabine, V.S.; Tovey, S.M.; Edwards, J.; Dunne, B.; Cooke, T.G.; Jones, F.E.; Bartlett, J.M.
Expression of tumor necrosis factor alpha converting enzyme in endocrine cancers (2008), Am. J. Clin. Pathol., 129, 735-743.

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Application

Application	Comment	Organism
medicine	the data presented herein show TACE expression in endocrine cancers and further support a role for TACE in breast cancer apoptosis	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
breast cancer cell line	TACE expression measured by immunohistochemical analysis is observed in 183 of 383 breast carcinomas. TACE expression is predominantly seen in tumors with high levels of released human epidermal growth factor-4 receptor intracellular domain (4ICD) and membranous human epidermal growth factor-4 receptor	Homo sapiens	-
ovary cancer cell line	TACE expression measured by immunohistochemical analysis is observed in 39 of 217 ovarian carcinomas.TACE expression is predominantly seen in tumors with high levels of released human epidermal growth factor-4 receptor intracellular domain (4ICD) and membranous human epidermal growth factor-4 receptor	Homo sapiens	-
prostate cancer cell line	TACE expression measured by immunohistochemical analysis is observed in 16 of 24 and 17 of 24 hormone-sensitive and hormone-insensitive prostate carcinomas. TACE expression is predominantly seen in tumors with high levels of released human epidermal growth factor-4 receptor intracellular domain (4ICD) and membranous human epidermal growth factor-4 receptor	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
TACE	-	Homo sapiens

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Release 2023.1 (January 2023)