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Literature summary for 3.4.24.86 extracted from

  • Sunnarborg, S.W.; Hinkle, C.L.; Stevenson, M.; Russell, W.E.; Raska, C.S.; Peschon, J.J.; Castner, B.J.; Gerhart, M.J.; Paxton, R.J.; Black, R.A.; Lee, D.C.
    Tumor necrosis factor-alpha converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability (2002), J. Biol. Chem., 277, 12838-12845.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
transfection of TACE into TACE deficient cells Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane membrane-bound Mus musculus 16020
-
membrane membrane-bound Homo sapiens 16020
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
mouse
-
Mus musculus
-
EC-2, clonal Ras/Myc-immortalized fibroblast cell line
-

Purification (Commentary)

Purification (Comment) Organism
-
Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast
-
Mus musculus
-
fibroblast
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
BTC + H2O
-
Mus musculus ?
-
?
EPR + H2O
-
Mus musculus ?
-
?
HB-EGF heparin binding epidermal growth factor + H2O
-
Mus musculus ?
-
?
additional information
-
Mus musculus ?
-
?
additional information amphiregulin is no substrate Homo sapiens ?
-
?
pro-TGF-alpha + H2O
-
Mus musculus mature growth factor
-
?
proTNF-alpha + H2O
-
Mus musculus soluble TNF-alpha
-
?
proTNF-alpha + H2O
-
Homo sapiens soluble TNF-alpha
-
?
transforming growth factor alpha + H2O
-
Mus musculus ?
-
?
transforming growth factor alpha + H2O
-
Homo sapiens ?
-
?