Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | fusion protein of N-terminal 27 amino acids deletion of protective antigen-binding domain of anthrax lethal factor Delta27LFn and protective antigen-binding domain of edema factor is a 62-fold more potent toxin inhibitor than protective antigen-binding domain of anthrax lethal factor or protective antigen-binding domain of edema factor in a cell model of intoxication, and this increased activity corresponds to a 39-fold higher protective antigen-binding affinity by Biacore analysis. The fusion protein can protect the highly susceptible Fischer 344 rats from anthrax lethal toxin challenge | Bacillus anthracis |
Organism | UniProt | Comment | Textmining |
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Bacillus anthracis | - |
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