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Literature summary for 3.4.24.81 extracted from
- Protocadherin-12 cleavage is a regulated process mediated by ADAM10 protein: evidence of shedding up-regulation in pre-eclampsia (2011), J. Biol. Chem., 286, 15195-15204.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| GI254023X | specifically inhibits ADAM10 | Homo sapiens |  |
| GW280264X | blocks both ADAM10 and ADAM17 | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| protocadherin + H2O | ADAM10 cleaves the extracellular domain of protocadherin | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| a disintegrin and metalloprotease 10 | - |
Homo sapiens |
| ADAM10 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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