Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L1 cell-adhesion molecule + H2O | Homo sapiens | the ectodomain of L1 cell-adhesion molecule is cleaved at the plasma membrane by ADAM10. Regulated proteolytic processing by ADAM10 and PS/gamma-secretase is essential for the nuclear signalling of L1 in human carcinoma cell lines | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L1 cell-adhesion molecule + H2O | - |
Homo sapiens | ? | - |
? | |
L1 cell-adhesion molecule + H2O | the ectodomain of L1 cell-adhesion molecule is cleaved at the plasma membrane by ADAM10. Regulated proteolytic processing by ADAM10 and PS/gamma-secretase is essential for the nuclear signalling of L1 in human carcinoma cell lines | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ADAM10 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | regulated proteolytic processing by ADAM10 and PS/gamma-secretase is essential for the nuclear signalling of L1 | Homo sapiens |