Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.24.35 extracted from

  • Awla, D.; Abdulla, A.; Syk, I.; Jeppsson, B.; Regner, S.; Thorlacius, H.
    Neutrophil-derived matrix metalloproteinase-9 is a potent activator of trypsinogen in acinar cells in acute pancreatitis (2011), J. Leukoc. Biol., 91, 711-719.
    View publication on PubMed
Search for more literature for 3.4.24.35

Inhibitors

Inhibitors Comment Organism Structure
BB-94 broad-spectrum MMP inhibitor Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-
Mus musculus C57BL/6
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information MMP-9 levels are increased in acute pancreatitis Mus musculus
-
neutrophil
-
 Mus musculus
-
pancreas
-
 Mus musculus
-
pancreatic acinar cell
-
 Mus musculus
-

Synonyms

Synonyms Comment Organism
matrix metalloproteinase-9
-
 Mus musculus
MMP-9
-
 Mus musculus

General Information

General Information Comment Organism
malfunction the broad-spectrum inhibitor of MMPs, BB-94, markedly reduces activation of trypsinogen, levels of CXCL2, infiltration of neutrophils, and tissue damage in acute pancreatitis Mus musculus
physiological function neutrophil-derived matrix metalloproteinase-9 is a potent activator of trypsinogen in acinar cells in acute pancreatitis Mus musculus