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Literature summary for 3.4.24.35 extracted from

  • Kim, S.; Choi, J.H.; Lim, H.I.; Lee, S.K.; Kim, W.W.; Kim, J.S.; Kim, J.H.; Choe, J.H.; Yang, J.H.; Nam, S.J.; Lee, J.E.
    Silibinin prevents TPA-induced MMP-9 expression and VEGF secretion by inactivation of the Raf/MEK/ERK pathway in MCF-7 human breast cancer cells (2009), Phytomedicine, 16, 573-580.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
breast cancer cell
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Homo sapiens
-
MCF-7 cell
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Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gelatin + H2O
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Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
matrix metalloproteinase-9
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Homo sapiens
MMP-9
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Homo sapiens

Expression

Organism Comment Expression
Homo sapiens 12-O-tetradecanoyl phorbol-13-acetate-induced MMP-9 expression is decreased by 324.8% by 0.1 mM silibinin down
Homo sapiens 10 nM 12-O-tetradecanoyl phorbol-13-acetate induces MMP-9 expression (9728.9% of the control) after 24 h by the suppression of the Raf/MEK/ERK pathway in MCF-7 human breast cancer cells, 12-O-tetradecanoyl phorbol-13-acetate-induced MMP-9 expression is significantly inhibited by UO126, but not by SP600125 and SB203580 up