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Literature summary for 3.4.24.35 extracted from
- PPARgamma agonist pioglitazone reduces matrix metalloproteinase-9 activity and neuronal damage after focal cerebral ischemia (2009), Biochem. Biophys. Res. Commun., 380, 17-21.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | the reduction of MMP-9 activity may have a possible therapeutic effect for the management of brain injury after focal ischemia | Mus musculus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| pioglitazone | pioglitazone reduces the upregulation of active form of MMP-9 after ischemia | Mus musculus |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 97000 | - |
active enzyme form, gelatin gel zymography | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Gelatin + H2O | - |
Mus musculus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| matrix metalloproteinase-9 | - |
Mus musculus |
| MMP-9 | - |
Mus musculus |
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