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Literature summary for 3.4.24.35 extracted from

  • Marco, M.; Baz, A.; Fernandez, C.; Gonzalez, G.; Hellman, U.; Salinas, G.; Nieto, A.
    A relevant enzyme in granulomatous reaction, active matrix metalloproteinase-9, found in bovine Echinococcus granulosus hydatid cyst wall and fluid (2006), Parasitol. Res., 100, 131-139.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+
-
Bos taurus
Zn2+
-
Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
84000
-
x * 92000, pro-MMP-9, SDS-PAGE, x * 84000, activated MMP-9, SDS-PAGE Bos taurus
92000
-
x * 92000, pro-MMP-9, SDS-PAGE, x * 84000, activated MMP-9, SDS-PAGE Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Gelatin + H2O Bos taurus
-
?
-
?
additional information Bos taurus active host MMP-9 is expressed in walls and fluids of hydatid cysts of parasite Echinococcus granulosus in the environment of granulomatous reaction, in vivo activation of MMP-9 suggests its involvement in inflammatory reaction and in the chemotaxis of inflammatory cells to the cyst. However, the parasite can deal efficiently with MMP-9, overview ?
-
?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
cattle infected with Echinococcus granulosus
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information active host MMP-9 is expressed in walls and fluids of hydatid cysts of parasite Echinococcus granulosus in the environment of granulomatous reaction, immunohistochemic analysis, positive reaction to MMP-9 is found in cyst-surrounding cells, epithelioid and giant cells, and in the germinal layer of cyst wall, overview Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gelatin + H2O
-
Bos taurus ?
-
?
Gelatin + H2O gelatin zymography, mass spectrometrical analysis, overview Bos taurus ?
-
?
additional information active host MMP-9 is expressed in walls and fluids of hydatid cysts of parasite Echinococcus granulosus in the environment of granulomatous reaction, in vivo activation of MMP-9 suggests its involvement in inflammatory reaction and in the chemotaxis of inflammatory cells to the cyst. However, the parasite can deal efficiently with MMP-9, overview Bos taurus ?
-
?

Subunits

Subunits Comment Organism
? x * 92000, pro-MMP-9, SDS-PAGE, x * 84000, activated MMP-9, SDS-PAGE Bos taurus

Synonyms

Synonyms Comment Organism
MMP-9
-
Bos taurus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Bos taurus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.6
-
assay at Bos taurus