Cloned (Comment) | Organism |
---|---|
expresssion of wild-type MMP-9 and truncated versions in insect cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
antibody REGA-3G12 | highly selective, potent MMP-9 inhibition, the antibody recognizes the N-terminal part, not the C-terminal hemopexin and O-glycosylated domains, epitope mapping, overview | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | a zinc metalloproteinase, contains one Zn2+ per enzyme molecule | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gelatin + H2O | Homo sapiens | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P14780 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | the enzyme is O-glycosylated at Trp116-Lys214 sequence of the C-terminal part | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gelatin + H2O | - |
Homo sapiens | ? | - |
? | |
Gelatin + H2O | gelatin zymography | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | epitope mapping, structure modeling, overview | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
matrix metalloproteinase-9 | - |
Homo sapiens |
MMP-9 | - |
Homo sapiens |