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Literature summary for 3.4.24.23 extracted from

  • Anand, S.P.; Selvaraj, P.
    Effect of 1, 25 dihydroxyvitamin D(3) on matrix metalloproteinases MMP-7, MMP-9 and the inhibitor TIMP-1 in pulmonary tuberculosis (2009), Clin. Immunol., 133, 126-131.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
TIMP-1 tissue inhibitor of metalloprotease-1 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
mononuclear cell frp, peripheral blood Homo sapiens
-

Synonyms

Synonyms Comment Organism
Matrix metalloproteinase-7
-
Homo sapiens
MMP-7
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens 1,25-dihydroxyvitamin D3, i.e. 1, 25(OH)2D3, significantly reduces the MMP-7 and MMP-9 and increases the TIMP-1 inhibitor level in Mycobacterium tuberculosis antigen stimulated and unstimulated mononuclear cell cultures of pulmonary tunerculosis patients as compared to healthy persons down
Homo sapiens Mycobacterium tuberculosis infection and its antigen cause an increase in MMP-7 expression in mononuclear cell cultures of pulmonary tunerculosis patients as compared to healthy persons untreated with 1,25-dihydroxyvitamin D3 up