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Literature summary for 3.4.24.23 extracted from

  • Ito, T.K.; Ishii, G.; Chiba, H.; Ochiai, A.
    The VEGF angiogenic switch of fibroblasts is regulated by MMP-7 from cancer cells (2007), Oncogene, 26, 7194-7203.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
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Homo sapiens
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-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens MMP-7 elicits endothelial tube formation, which is abrogated by anti-VEGF antibody or connective tissue growth factor, cancer cell MMP-7 regulates the VEGF activity in colorectal tissue and VEGF angiogenic switch of fibroblasts, overview, suppression of MMP-7 in Capan-1 cells abrogates the tumor angiogenic activity of VA-13 fibroblasts, which is restored by suppression of CTGF in VA-13 fibroblasts ?
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?

Organism

Organism UniProt Comment Textmining
Homo sapiens P09237
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-

Source Tissue

Source Tissue Comment Organism Textmining
carcinoma cell
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Homo sapiens
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fibroblast stromal Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information MMP-7 elicits endothelial tube formation, which is abrogated by anti-VEGF antibody or connective tissue growth factor, cancer cell MMP-7 regulates the VEGF activity in colorectal tissue and VEGF angiogenic switch of fibroblasts, overview, suppression of MMP-7 in Capan-1 cells abrogates the tumor angiogenic activity of VA-13 fibroblasts, which is restored by suppression of CTGF in VA-13 fibroblasts Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
Matrix metalloproteinase-7
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Homo sapiens
MMP-7
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Homo sapiens