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Literature summary for 3.4.24.23 extracted from

  • Yamamoto, K.; Higashi, S.; Kioi, M.; Tsunezumi, J.; Honke, K.; Miyazaki, K.
    Binding of active matrilysin to cell surface cholesterol sulfate is essential for its membrane-associated proteolytic action and induction of homotypic cell adhesion (2006), J. Biol. Chem., 281, 9170-9180.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
recombinant enzyme
-

Subunits

Subunits Comment Organism
More enzyme binds to cholesterol sulfate on cell surface. Treatment of colon cancer cells with beta-cyclodextrin significantly reduces both enzyme binding to cell surface and enzyme-dependent proteolysis and cell aggregation Homo sapiens