Literature summary for 3.4.24.23 extracted from

Wang, F.; Reierstad, S.; Fishman, D.A.
Matrilysin over-expression in MCF-7 cells enhances cellular invasiveness and pro-gelatinase activation (2006), Cancer Lett., 236, 292-301.

Application

Application	Comment	Organism
medicine	overexpression of enzyme correlates with breast cancer in vitro invasiveness, enzyme may promote invasion by increasing the secretion and activation of matrix metalloproteinases proMMP-2 and pro-MMP-9	Homo sapiens

Organism	UniProt	Comment	Textmining
Homo sapiens	-	expression in MCF-7 breast cancer cell. Overexpression of enzyme leads to increased invasion and gelatinase activation	-

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Release 2023.1 (January 2023)