Organism | UniProt | Comment | Textmining |
---|---|---|---|
Danio rerio | Q6NZT7 | - |
- |
Source Tissue | Comment | Organism | Textmining |
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General Information | Comment | Organism |
---|---|---|
physiological function | homozygous bace1 mutants are hypomyelinated in the peripheral nervous system while the central nervous system is not affected. The number of mechanosensory neuromasts is elevated. Double homozygous Bace1/Bace2 fish do not enhance the single mutant phenotypes indicating non-redundant distinct physiological functions. Single homozygous bace1 mutants as well as double homozygous bace1 and bace2 mutants are viable and fertile | Danio rerio |