Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-(2-chlorobenzyl)-4-(4-(dibenzo[b,d]furan-1-yl)benzyl)-1H-imidazol-2-amine | 0.005 mM, 37.8% inhibition. Inhibitor is predicted to be able to cross the blood-brain barrier | Homo sapiens | |
1-(4-fluorobenzyl)-4-((30,50-dimethoxybiphenyl-4-yl)methyl)-1H-imidazol-2-amine | 0.005 mM, 40% inhibition. Inhibitor is predicted to be able to cross the blood-brain barrier | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(7-methoxycoumarin-4-yl)acetyl-L-Ser-L-Glu-L-Val-L-Asn-L-Leu-L-Asp-L-Ala-L-Glu-L-Phe-L-Lys-dinitrophenyl + H2O | - |
Homo sapiens | ? | - |
? |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0056 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 1-(4-fluorobenzyl)-4-((30,50-dimethoxybiphenyl-4-yl)methyl)-1H-imidazol-2-amine | |
0.0059 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 1-(2-chlorobenzyl)-4-(4-(dibenzo[b,d]furan-1-yl)benzyl)-1H-imidazol-2-amine |