Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(+)-byakangelicin | - |
Homo sapiens | |
(+)-byakangelicol | - |
Homo sapiens | |
(+)-oxypeucedanin | - |
Homo sapiens | |
imperatorin | strongest inhibition of BACE1 activity | Homo sapiens | |
isoimperatorin | - |
Homo sapiens | |
Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-(statine)-Val-Ala-Glu-Phe-OH | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
rhodamine-EVNLDAEFK-quencher + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
BACE1 | - |
Homo sapiens |
beta-secretase | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0002 | - |
in 50 mM sodium acetate, pH 4.5, at 25°C | Homo sapiens | Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-(statine)-Val-Ala-Glu-Phe-OH | |
0.0918 | - |
in 50 mM sodium acetate, pH 4.5, at 25°C | Homo sapiens | imperatorin | |
0.1049 | - |
in 50 mM sodium acetate, pH 4.5, at 25°C | Homo sapiens | (+)-byakangelicol | |
0.2197 | - |
in 50 mM sodium acetate, pH 4.5, at 25°C | Homo sapiens | (+)-byakangelicin | |
0.2442 | - |
in 50 mM sodium acetate, pH 4.5, at 25°C | Homo sapiens | isoimperatorin | |
0.3592 | - |
in 50 mM sodium acetate, pH 4.5, at 25°C | Homo sapiens | (+)-oxypeucedanin |