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Literature summary for 3.4.23.46 extracted from

  • Laird, F.M.; Cai, H.; Savonenko, A.V.; Farah, M.H.; He, K.; Melnikova, T.; Wen, H.; Chiang, H.C.; Xu, G.; Koliatsos, V.E.; Borchelt, D.R.; Price, D.L.; Lee, H.K.; Wong, P.C.
    BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions (2005), J. Neurosci., 25, 11693-11709.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
amyloid beta-precursor protein + H2O Mus musculus BACE1 and the amyloid beta-precursor protein processing pathway are critical for cognitive, emotional and synaptic functions ?
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?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
amyloid beta-precursor protein + H2O BACE1 and the amyloid beta-precursor protein processing pathway are critical for cognitive, emotional and synaptic functions Mus musculus ?
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?

Synonyms

Synonyms Comment Organism
BACE1
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Mus musculus