Literature summary for 3.4.23.46 extracted from

Tomasselli, A.G.; Qahwash, I.; Emmons, T.L.; Lu, Y.; Leone, J.W.; Lull, J.M.; Fok, K.F.; Bannow, C.A.; Smith, C.W.; Bienkowski, M.J.; Heinrikson, R.L.; Yan, R.
Employing a superior BACE1 cleavage sequence to probe cellular APP processing (2003), J. Neurochem., 84, 1006-1017.

Search for more literature for 3.4.23.46

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
amyloid precursor protein + H2O	i.e. APP, cleavage occurs between VKM-DA	Homo sapiens	?	-	?
additional information	APP mutants with superior cleavage sites	Homo sapiens	?	-	?
oxidized insulin B chain + H2O	-	Homo sapiens	?	-	?
Swedish variant of amyloid precursor protein + H2O	i.e. APPSw	Homo sapiens	?	-	?
ubiquitin + H2O	-	Homo sapiens	?	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)