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Literature summary for 3.4.23.46 extracted from

  • Ehehalt, R.; Michel, B.; De Pietri Tonelli, D.; Zacchetti, D.; Simons, K.; Keller, P.
    Splice variants of the beta-site APP-cleaving enzyme BACE1 in human brain and pancreas (2002), Biochem. Biophys. Res. Commun., 293, 30-37.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum isoforms BACE1B, BACE1C, both without beta-secretase activity Homo sapiens 5783
-
Golgi apparatus post-Golgi membranes, isoforms BACE1A, BACE2 Homo sapiens 5794
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain isoform BACE1B Homo sapiens
-
pancreas isoforms BACE1B and BACE1C Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
amyloid precursor protein + H2O
-
Homo sapiens ?
-
?
additional information residue specificity of memapsin 1 subsites Homo sapiens ?
-
?
Swedish variant of amyloid precursor protein + H2O
-
Homo sapiens ?
-
?