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Literature summary for 3.4.23.3 extracted from
- Pepsinogen C and pepsin C from gastric mucosa of Japanese monkey. Purification and characterization (1976), J. Biochem., 80, 983-992.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,2-epoxy-3-(p-nitrophenoxy)propane | - |
Macaca fuscata |  |
| Diazoacetyl-DL-norleucine methyl ester | - |
Macaca fuscata | |
| p-bromophenylacyl bromide | - |
Macaca fuscata | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 27000 | - |
the MW of pepsinogen C is 35000 Da, gel filtration | Macaca fuscata |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Macaca fuscata | - |
fuscata | - |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| no modification | contains no carbohydrate | Macaca fuscata |
| proteolytic modification | zymogen: pepsinogen C | Macaca fuscata |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| gastric mucosa | - |
Macaca fuscata | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Hemoglobin + H2O | - |
Macaca fuscata | ? | - |
? | |
| N-acetyl-L-phenylalanyl-L-diiodotyrosine + H2O | scarcely hydrolyzed | Macaca fuscata | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 3 | - |
hemoglobin | Macaca fuscata |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 1.2 | 3.5 | pH 1.2: about 75% of maximal activity, pH 3.5: about 55% of maximal activity | Macaca fuscata |
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