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Literature summary for 3.4.23.15 extracted from

  • Solomon, S.D.; Appelbaum, E.; Manning, W.J.; Verma, A.; Berglund, T.; Lukashevich, V.; Cherif Papst, C.; Smith, B.A.; Dahloef, B.; Dahloef, B.
    Effect of the direct renin inhibitor aliskiren, the angiotensin receptor blocker losartan, or both on left ventricular mass in patients with hypertension and left ventricular hypertrophy (2009), Circulation, 119, 530-537.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
aliskiren orally active direct renin inhibitor Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
angiotensinogen + H2O Homo sapiens
-
angiotensin I + angiotensinogen propeptide
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
angiotensinogen + H2O
-
Homo sapiens angiotensin I + angiotensinogen propeptide
-
?