Application | Comment | Organism |
---|---|---|
medicine | blockade of renin activation is a therapeutic target to prevent glomerular injury and associated proteinuria | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
aliskiren | potent direct renin inhibitor | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensinogen + H2O | Rattus norvegicus | - |
angiotensin I + angiotensinogen propeptide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensinogen + H2O | - |
Rattus norvegicus | angiotensin I + angiotensinogen propeptide | - |
? |
General Information | Comment | Organism |
---|---|---|
metabolism | renin is the rate-limiting step in angiotensin II generation | Rattus norvegicus |