Literature summary for 3.4.23.15 extracted from

Takahashi, S.; Hori, K.; Shinbo, M.; Hiwatashi, K.; Gotoh, T.; Yamada, S.
Isolation of human renin inhibitor from soybean: soyasaponin I is the novel human renin inhibitor in soybean (2008), Biosci. Biotechnol. Biochem., 72, 3232-3236.

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Cloned(Commentary)

Cloned (Comment)	Organism
-	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
soyasaponin I	i.e. soybean renin inhibitor. Significant inhibition of recombinant renin, partially noncompetitive	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.0375	-	soyasaponin I	pH 6.5, 37°C	Homo sapiens

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
additional information	-	IC50 value 30 microg/ml at pH 6.5, 37°C	Homo sapiens	soyasaponin I

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Release 2023.1 (January 2023)