Literature summary for 3.4.23.15 extracted from

Unger, N.; Lopez Schmidt, I.; Pitt, C.; Walz, M.K.; Philipp, T.; Mann, K.; Petersenn, S.
Comparison of active renin concentration and plasma renin activity for the diagnosis of primary hyperaldosteronism in patients with an adrenal mass (2004), Eur. J. Endocrinol., 150, 517-523.

Search for more literature for 3.4.23.15

Application

Application	Comment	Organism
diagnostics	comparison of active renin concentration and plasma renin activity for the diagnosis of primary hyperaldosteronism in patients with an adrenal mass, the ratio of plasma renin activity to plasma aldosterone concentration is a screening test for primary hyperaldosteronism	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
extracellular	plasma	Homo sapiens	-	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
angiotensinogen + H2O	Homo sapiens	the ratio of plasma renin activity to plasma aldosterone concentration is a screening test for primary hyperaldosteronism, overview	angiotensin I + angiotensinogen propeptide	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	healthy persons, hypertensive patients, and patients with aldosterone- and/or cortisol secreting adenomas	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
blood plasma	plasma renin activity, PRA, and active renin concentration, ARC, overview	Homo sapiens	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
additional information	-	plasma renin activity, PRA, and active renin concentration, ARC, of healthy persons, hypertensive patients, and patients with aldosterone- and/or cortisol secreting adenomas, overview	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
angiotensinogen + H2O	-	Homo sapiens	angiotensin I + angiotensinogen propeptide	-	?
angiotensinogen + H2O	the ratio of plasma renin activity to plasma aldosterone concentration is a screening test for primary hyperaldosteronism, overview	Homo sapiens	angiotensin I + angiotensinogen propeptide	-	?

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Release 2023.1 (January 2023)