Literature summary for 3.4.22.56 extracted from

Margolin, N.; Raybuck, S.A.; Wilson, K.P.; Chen, W.; Fox, T.; Gu, Y.; Livingston, D.J.
Substrate and inhibitor specificity of interleukin-1beta-converting enzyme and related caspases (1997), J. Biol. Chem., 272, 7223-7228.

Inhibitors

Inhibitors	Comment	Organism	Structure
acetyl-DEVD-aldehyde	-	Homo sapiens

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
poly(ADP-ribose) polymerase + H2O	very high cleavage	Homo sapiens	?	-	?

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.00000052	-	acetyl-DEVD-aldehyde	pH 7.5	Homo sapiens

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Release 2023.1 (January 2023)