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Literature summary for 3.4.22.52 extracted from
- Over-expression of calpastatin inhibits calpain activation and attenuates myocardial dysfunction during endotoxaemia (2009), Cardiovasc. Res., 83, 72-79.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| calpastatin | highly specific inhibitor of calpain-1 and calpain-2 | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cardiomyocyte | - |
Rattus norvegicus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| calpain-1 (micro-form) | - |
Rattus norvegicus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | gp91phox-NADPH oxidase-mediated calpain-1 activation induces caspase-3 activation and tumour necrosis factor-alpha expression in cardiomyocytes during lipopolysaccaride stimulation | Rattus norvegicus |
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Release 2023.1 (January 2023)
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