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Literature summary for 3.4.22.52 extracted from
- Hyperglycemia is a major determinant of albumin permeability in diabetic microcirculation: the role of mu-calpain (2007), Diabetes, 56, 1842-1849.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | role for the mu-calpain isoform in the hypermeability of the diabetic endothelium. mu-calpain is the molecular target of the endothelial protective action of pharmacological calpain inhibition in vivo | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Rattus norvegicus | role for mu-calpain isoform in the hypermeability of the diabetic endothelium | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | role for mu-calpain isoform in the hypermeability of the diabetic endothelium | Rattus norvegicus | ? | - |
? | |
| N-succinyl-L-leucyl-L-valyl-L-tyrosinyl-7-amido-4-methylcoumarin + H2O | - |
Rattus norvegicus | ? | - |
? | |
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Release 2023.1 (January 2023)
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