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Literature summary for 3.4.22.52 extracted from

  • Shastri, R.; Anandaraj, M.P.J.S.
    A low-calcium-requiring calcium-activated neutral proteinase from human placenta (1986), Biochim. Biophys. Acta, 873, 260-266.
    View publication on PubMed
Search for more literature for 3.4.22.52

Activating Compound

Activating Compound Comment Organism Structure
2-mercaptoethanol required for maximal activity Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information
-
 Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
EDTA 0.25 mM, complete Homo sapiens
iodoacetic acid 0.25 mM, complete Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ half-maximal activity at 0.04 mM, maximal activity at 0.1 mM Homo sapiens
Mn2+ synergistic acivation in combination with Ca2+ Homo sapiens
Sr2+ synergistic acivation in combination with Ca2+ Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
32000
-
 1 * 74000 + 1 * 32000, SDS-PAGE Homo sapiens
74000
-
 1 * 74000 + 1 * 32000, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
placenta
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Homo sapiens

Subunits

Subunits Comment Organism
dimer 1 * 74000 + 1 * 32000, SDS-PAGE Homo sapiens
More EC 3.4.22.52 is not derived by the autolysis of EC 3.4.22.53, but it is an independent species Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
-
 Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
 Homo sapiens