Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Val-Ala-Asp | - |
Homo sapiens | |
YVAD | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Bap31 protein + H2O | Homo sapiens | - |
? | - |
? | |
pro-interleukin-18 + H2O | Homo sapiens | - |
interleukin-18 propeptide | - |
? | |
pro-interleukin-1beta + H2O | Homo sapiens | - |
interleukin-1beta propeptide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
keratinocyte | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Bap31 protein + H2O | - |
Homo sapiens | ? | - |
? | |
pro-interleukin-18 + H2O | - |
Homo sapiens | interleukin-18 propeptide | - |
? | |
pro-interleukin-1beta + H2O | - |
Homo sapiens | interleukin-1beta propeptide | - |
? |
General Information | Comment | Organism |
---|---|---|
physiological function | caspase-1 activity is required for UVB-induced apoptosis of human keratinocytes and therefore plays a protective role of the protease in UVB-induced skin cancer development | Homo sapiens |