Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
pro-interleukin-1beta + H2O | Mus musculus | - |
interleukin-1beta propeptide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
microglia | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pro-interleukin-1beta + H2O | - |
Mus musculus | interleukin-1beta propeptide | - |
? |
General Information | Comment | Organism |
---|---|---|
physiological function | lysosomal swelling and mitochondrial impairment contribute to caspase-1 activation and to the consequent interleukin-1beta release | Mus musculus |