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Literature summary for 3.4.22.36 extracted from
- Role of caspase-1 and interleukin-1beta in acetaminophen-induced hepatic inflammation and liver injury (2010), Toxicol. Appl. Pharmacol., 247, 169-178.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Cbz-Val-Asp-fluoromethylketone | increase in IL-1beta protein levels in a liver injury mouse model is completely prevented with the pan-caspase inhibitor demonstrating the efficacy of Cbz-Val-Asp-fluoromethylketone to block caspase-1 activity | Mus musculus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| caspase-1 | - |
Mus musculus |
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Release 2023.1 (January 2023)
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