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Literature summary for 3.4.22.36 extracted from

  • Sarkar, A.; Mitra, S.; Mehta, S.; Raices, R.; Wewers, M.D.
    Monocyte derived microvesicles deliver a cell death message via encapsulated caspase-1 (2009), PLoS ONE, 4, e7140.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.22.36

Inhibitors

Inhibitors Comment Organism Structure
L-Tyr-L-Val-L-Ala-L-Asp-chloromethylketone
-
 Homo sapiens
Z-L-Val-L-Ala-L-Asp-(O-methyl)-fluoromethylketone
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
pro-interleukin-1beta + H2O Homo sapiens
-
 mature interleukin-1beta + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
monocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pro-interleukin-1beta + H2O
-
 Homo sapiens mature interleukin-1beta + ?
-
 ?

Synonyms

Synonyms Comment Organism
IL-1 converting enzyme
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function caspase-1 mediates cell death, monocytes are capable of delivering a cell death message which depends upon the release of microvesicles containing functional caspase-1. Encapsulation is necessary for exogenous caspase-1 induced cell death Homo sapiens