Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | the inflammasome activator ATP can induce the production of reactive oxygen species, which are important for caspase-1 activation | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
carbobenzoxy-L-valyl-L-alanyl-L-aspartyl-[O-methyl]-fluoromethylketone | caspase-1-specific inhibitor | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
pro-interleukin-1beta + H2O | Homo sapiens | - |
mature interleukin-1beta + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
THP-1 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pro-interleukin-1beta + H2O | - |
Homo sapiens | mature interleukin-1beta + ? | - |
? |