Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | caspase-1 activation induced by MDP and ATP requires pore-forming pannexin-1, for delivery of the inducer MDP into the cell, and cryopyrin but is independent of Nod2 and NF-kappaB and MAPK signaling | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | caspase-1 activation induced by MDP and ATP requires pore-forming pannexin-1, for delivery of the inducer MDP into the cell, and cryopyrin but is independent of Nod2 | ? | - |
? | |
additional information | Mus musculus C57BL/6 | caspase-1 activation induced by MDP and ATP requires pore-forming pannexin-1, for delivery of the inducer MDP into the cell, and cryopyrin but is independent of Nod2 | ? | - |
? | |
pro-interleukin-18 + H2O | Mus musculus | - |
interleukin-18 + ? | - |
? | |
pro-interleukin-18 + H2O | Mus musculus C57BL/6 | - |
interleukin-18 + ? | - |
? | |
pro-interleukin-1beta + H2O | Mus musculus | - |
interleukin-1beta + ? | - |
? | |
pro-interleukin-1beta + H2O | Mus musculus C57BL/6 | - |
interleukin-1beta + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
C57BL/6 mice | - |
Mus musculus C57BL/6 | - |
C57BL/6 mice | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | caspase-1 activation induced by MDP and ATP requires pore-forming pannexin-1, for delivery of the inducer MDP into the cell, and cryopyrin but is independent of Nod2 | Mus musculus | ? | - |
? | |
additional information | caspase-1 activation induced by MDP and ATP requires pore-forming pannexin-1, for delivery of the inducer MDP into the cell, and cryopyrin but is independent of Nod2 | Mus musculus C57BL/6 | ? | - |
? | |
pro-interleukin-18 + H2O | - |
Mus musculus | interleukin-18 + ? | - |
? | |
pro-interleukin-18 + H2O | - |
Mus musculus C57BL/6 | interleukin-18 + ? | - |
? | |
pro-interleukin-1beta + H2O | - |
Mus musculus | interleukin-1beta + ? | - |
? | |
pro-interleukin-1beta + H2O | - |
Mus musculus C57BL/6 | interleukin-1beta + ? | - |
? |