Application | Comment | Organism |
---|---|---|
medicine | ICE activity is a possible target for fighting excessive inflammatory conditions | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | in brain microvascular endothelial cells and in astrocytes expression and activity of inducible nitric axide synthase exclusively depends on the endogenous availability of bioactive interleukin-1beta as inhibition of ICE activity significantly decreases promoter activity of inducible nitric axide synthase, expression and enzyme activity | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
astrocyte | - |
Rattus norvegicus | - |
brain microvascular endothelial cell | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | in brain microvascular endothelial cells and in astrocytes expression and activity of inducible nitric axide synthase exclusively depends on the endogenous availability of bioactive interleukin-1beta as inhibition of ICE activity significantly decreases promoter activity of inducible nitric axide synthase, expression and enzyme activity | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ICE | - |
Rattus norvegicus |
interleukin-1-converting enzyme | - |
Rattus norvegicus |