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Literature summary for 3.4.22.28 extracted from

  • Lei, X.; Xiao, X.; Xue, Q.; Jin, Q.; He, B.; Wang, J.
    Cleavage of interferon regulatory factor 7 by enterovirus 71 3C suppresses cellular responses (2013), J. Virol., 87, 1690-1698.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
interferon regulatory factor 7 + H2O Enterovirus A71 cleavage occurs at the Q189-S190 junction within the constitutive activation domain ?
-
?
TRIF protein + H2O Enterovirus A71
-
?
-
?

Organism

Organism UniProt Comment Textmining
Enterovirus A71
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
interferon regulatory factor 7 + H2O cleavage occurs at the Q189-S190 junction within the constitutive activation domain Enterovirus A71 ?
-
?
TRIF protein + H2O
-
Enterovirus A71 ?
-
?

Synonyms

Synonyms Comment Organism
3C protease
-
Enterovirus A71

General Information

General Information Comment Organism
physiological function the control of interferon regulatory factor 7 by 3C protease represents a viral mechanism to escape cellular responses Enterovirus A71