Application | Comment | Organism |
---|---|---|
medicine | conservation of critical amino acid residues in 3C protease and the potent, broad-spectrum activity of rupintrivir highlight the advantage of 3C protease as an antiviral target | enterovirus |
medicine | conservation of critical amino acid residues in 3C protease and the potent, broad-spectrum activity of rupintrivir highlight the advantage of 3C protease as an antiviral target | Human rhinovirus sp. |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
rupintrivir | irreversible inhibitor of human enterovirus strains (4 of 4) | enterovirus | |
rupintrivir | potent in vitro activity against 23 clinical isolates tested in H1-HeLa cell protection assays | Human rhinovirus sp. |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
enterovirus | - |
and strains CVB5, EV6, and EV9 | - |
enterovirus CVB2 | - |
and strains CVB5, EV6, and EV9 | - |
Human rhinovirus sp. | - |
23 clinical isolates | - |
Synonyms | Comment | Organism |
---|---|---|
3C protease | - |
enterovirus |
3C protease | - |
Human rhinovirus sp. |