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Literature summary for 3.4.22.2 extracted from

  • Li, S.; Tang, Y.
    Accurate determination of internalization for target binding antibody using papain digestion and flow cytometry (2010), Hybridoma, 29, 133-139.
    View publication on PubMed

Application

Application Comment Organism
medicine method for internalization of monoclonal antibodies based on papain digestion followed by flow cytometry. This method can identify whether the binding monoclonal antibody has internalized into the cell, with an additional advantage of accurately quantifying the internalized monoclonal antibody without altering cell morphology after papain digestion. The methodology can facilitate understanding of the efficiency of monoclonal antibody internalization and evaluation of the targeted killing capacity of the monoclonal antibody Carica papaya

Organism

Organism UniProt Comment Textmining
Carica papaya
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